Genetics Syllabus

HUMAN GENETICS COURSE OUTLINE

HUMAN GENETICS COURSE OUTLINE  '09-'10

 

I.              MENDELIAN GENETICS (chapter 4 pages 70-83)

A.      Mendel's Principles

B.       One/two trait crosses

C.       Nature vs. nurture  (chapter 7 pp.131-145)

D.      pedigrees p 81-83

E.       post-Mendelian concepts (chapter 5 pages 89-96)

 

 

II.            DNA/RNA/PROTEIN SYNTHESIS (chapter 9 pages 166-175, chapter 10 pages 179-189)

A.      History (Watson, Crick, Franklin, Wilkins) (pages 166-169)

B.       Structure/function (pages 169-175)

C.       Basic protein synthesis (pages 180-186)

D.      Human Genome (Project) (page 206-208, 432)

               

III.           CELL DIVISION (pages 28-33)   

A.  Mitosis (pages 28,29,38,39)

B.  Cell growth (pages 28-32)

C.  Cancer (chapter 18-pages 353-373)

D.  Cloning (pages 36,37,52,53,380,381)

E.  Karyotypes (pages 241-242, 261)

 

IV.           GENETIC ENGINEERING (chapters 19 & 20 pages 375-400) Recombinant DNA (page 379)

A.      Gene therapy (pages 400)

B.       RFLP technology (pages 271,430,431)

C.       PCR (pages 377-378)

D.      Future prospects (Chapter 22 pages 429-439)

 

V.            DISEASES AND DISORDERS (see below)

A.      Autosomal Dominant and Recessive (pages 74-79 )

B.       Sex-Linked (pages 115,116)

C.       Polygenic/Multifactorial (132-141)

D.      Chromosomal (pages 247-60)

E.       Enzyme pathway disorders (pages 19,89,244)

 

VI.              SEX RELATED GENETICS (chapter 6 pages 107-126)

A.      Sex-determination (pages 108,109)

B.       Meiosis and ploidy (pages 41-50, 247)

C.       Abnormalities related to sex  p.341

D.      Reproductive technologies (pages 413-423)

 

VII.       BLOOD GENETICS (see below)

A.      ABO, Rh(D), MN groups (pages 91,92,96)

B.       Immune system (HLA groups) (pages 329,330-332)

C.       Transfusions (pages 329-330)

D.      Transplants (pages 345-347)

 

VIII.    BIOETHICS (p.2,10-13, 36-37, 113, 153, 276-278, 397-399)

A.        Bioethics vocabulary (class notes)

B.         Continuum of opinion (class notes)

C.         Bioethics issues (pages 2, 12, 15, 40, 70-71, 132, 167, 230, 318, 347, 384, 404, 421, 434-436)